OMAHA, January 14, 2008 — Researchers at the University of Nebraska Medical Center (UNMC), in collaboration with scientists at Affymetrix, have discovered a novel way to derive sequences for microarrays, resulting in the first ever commercially available whole-genome rhesus macaque microarray. This advance in primate genome research may help researchers to better understand the evolutionary relationship between primates and humans, and will increase the utility of rhesus macaque as a model organism for disease research
Rob Norgren and his collaborators used human transcript annotation to design primers to amplify and sequence rhesus genes. In collaboration with Affymetrix, this strategy was extended to an in silico approach using information… READ MORE



LONDON, December 17, 2007 — Researchers at Queen Mary, University of London have developed a new technique that combines three previously available technologies to quickly and precisely identify DNA rearrangements associated with tumor formation and growth. This new approach, which utilizes M-FISH, high-resolution karyotyping and exon array analysis, may help researchers identify critical candidate genes and genetic markers and better understand the role of complex genetic changes in human cancers.
JACKSONVILLE, Fla., October 29, 2007— A team of researchers from the United States, Germany and Sweden has discovered that the age of onset and severity of Parkinson’s disease (PD) in a large Swedish family is associated with the number of copies of a single gene. The finding suggests that lowering expression of the gene, or the protein it encodes, may one day protect carriers from this devastating neurodegenerative disease.

